Use of Hydroxyurea in Pediatric Patients with Sickle Cell Disease

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CLINICAL PRACTICE GUIDELINE SERIES.

Hydroxyurea is a myelosuppressive agent that has become a standard therapy for both pediatric and adult patients with sickle cell anemia (SCA), genotypes HbSS and HbSβ0, regardless of disease severity. 1 For pediatric patients, hydroxyurea has an acceptable short- term toxicity profile with the main side effect being mild, transient and reversible myelosuppression…

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Evidence Based Management of Sickle Cell Disease

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Prevention and Treatment of Stroke for Pediatric Patients with Sickle Cell Disease